Anybody seen the show Osmosis Jones ?
I find it rather crazy but entertaining. The show is a mix of real life and animation. It is about this guy Frank and the city in his body which is exactly like the real life city. The police in the city is the white blood cell and the bad guys are naturally the virus and germs.

Chris Rock is the voice bhind the hero and Bill Murray is Frank. The plot is so so but it is entertaining and Funny live-action give it a humorous touch.

It's laugh all the way .....